Overview / Definition
SSD RP (Topical) is a topical antimicrobial cream containing Silver Sulfadiazine used to prevent and treat infections in second- and third-degree burns and other skin wounds.
Causes or Mechanism
Silver sulfadiazine disrupts bacterial cell walls and interferes with DNA and protein synthesis; silver ions provide broad antimicrobial effects.
Signs & Symptoms (Indications)
- Prevention and treatment of burn wound infections.
- Management of infected wounds and ulcers.
- Use on skin graft donor sites.
- Prevention of infections in chronic skin ulcers.
Diagnosis
Based on clinical evaluation of wound type, depth, and infection signs.
Treatment / Management
- Apply a thin layer once or twice daily after cleaning.
- Continue until healing or as advised.
- Avoid contact with eyes and mucous membranes.
Side Effects
- Local irritation, burning, itching.
- Skin discoloration.
- Rare allergic reactions.
- Potential systemic absorption in large burns.
Warnings and Precautions
- Avoid in sulfa allergy.
- Use cautiously in pregnancy and breastfeeding.
- Avoid prolonged use on large areas without supervision.
Drug Interactions
Minimal; monitor concurrent sulfonamide use.
FAQs
- Can I use on minor cuts?
Primarily for burns and severe wounds. - Healing time?
Varies; SSD prevents infection but does not accelerate tissue growth. - Can I use under bandages?
Yes. - Is it safe for children?
Yes, under supervision. - Rash occurs?
Stop and consult doctor.
References
- https://medlineplus.gov/druginfo/meds/a682597.html
- https://www.mayoclinic.org/diseases-conditions/burns/diagnosis-treatment/drc-20370502
- https://www.drugs.com/mtm/silver-sulfadiazine-topical.html