The drug is usually used for the treatment of distinct or separate infections caused by different or several types of organism listed below
upper-respiratory-tract infections Otitis Media –acute or chronic otitis media caused by H. influenzae or M. catarrhalis.
tonsillitis and pharyngeal suppuration
Sinusitis – acute or chronic sinusitis caused by H. influenzae and M. catarrhalis.
Skin and Skin Structure Infections.
Lower Respiratory Tract Infections of H. influenzae and M. catarrhalis.
UTI (Urinary Tract Infections) – caused by β-lactamase–producing strains of E. coli, Klebsiella spp. and Enterobacter spp.
The drug is usually used for the treatment of distinct or separate infections caused by different or several type of organism listed below
upper-respiratory-tract infections Otitis Media –acute or chronic otitis media caused by H. influenzae or M. catarrhalis.
tonsillitis and pharyngeal suppuration
Sinusitis – acute or chronic sinusitis caused by H. influenzae and M. catarrhalis.
Skin and Skin Structure Infections.
Lower Respiratory Tract Infections of H. influenzae and M. catarrhalis.
UTI (Urinary Tract Infections) – caused by β-lactamase–producing strains of E. coli, Klebsiella spp. and Enterobacter spp.
SERIOUS AND OCCASIONALLY FATAL ALLERGIC REACTION (ANAPHYLACTIC) Allergic
reaction HAVE BEEN REPORTED IN PATIENTS ON PENICILLIN-ANTIBIOTICS THERAPY.
THESE Allergic reactions ARE MORE LIKELY TO OCCUR IN INDIVIDUALS WITH A HISTORY
OF
PENICILLIN-ANTIBIOTICS ALLERGIC REACTION AND/OR A HISTORY OF SENSITIVITY TO
MULTIPLE
ALLERGENS. THERE HAVE BEEN REPORTS OF INDIVIDUALS WITH A HISTORY OF
PENICILLIN-ANTIBIOTICS ALLERGIC REACTION WHO HAVE EXPERIENCED SEVERE
REACTIONS WHEN
TREATED WITH CEPHALOSPORINS. BEFORE INITIATING THERAPY WITH AUGMENTIN,
CAREFUL INQUIRY SHOULD BE MADE CONCERNING PREVIOUS ALLERGIC
REACTIONAllergic reaction TO PENICILLIN-ANTIBIOTICS, CEPHALOSPORINS, OR OTHER
ALLERGENS. IF AN
ALLERGIC REACTION OCCURS, the drug must be DISCONTINUED AND THE
APPROPRIATE THERAPY INSTITUTED. SERIOUS ANAPHYLACTIC REACTIONS
REQUIRE EMERGENCY TREATMENT WITH EPINEPHRINE. OXYGEN,
IV STEROIDS, AND AIRWAY MANAGEMENT, INCLUDING INTUBATION,
SHOULD ALSO BE ADMINISTERED AS INDICATED.
Augmentin 80/11.4 Syrup Amoxicillin 80 MG/ML / Clavulanate 11.4 MG/ML Oral Suspension Augmentin syrup Information Indication of Augmentin Augmentin dosage Side effect of Augmentin syrup More information Drug news Other…
AUGMENTIN is indicated in the treatment of different infections caused by various type of organism listed below
Lower Respiratory Tract Infections of H. influenzae and M. catarrhalis.
Otitis Media –acute or chronic otitis media caused by H. influenzae or M. catarrhalis.
tonsillitis and pharyngeal suppuration
Sinusitis – acute or chronic sinusitis caused by H. influenzae and M. catarrhalis.
Skin and Skin Structure Infections.
UTI (Urinary Tract Infections) – caused by β-lactamase–producing strains of E. coli, Klebsiella spp. and Enterobacter spp.
Augmentin is indicated just for the infections listed above, infections caused by ampicillin and amoxicillin-antibiotic sensitive organism are also sensitive and response will to treatment with the Augmentin due to its amoxicillin content.
so, mixed infections caused by ampicillin and amoxicillin-antibiotic sensitive organism and β-lactamase bacteria sensitive to drugs mostly require the addition of another antibiotic.
Because amoxicillin-antibiotic has greater in vitro activity against S. pneumoniae than does ampicillin or penicillin, most of S. pneumoniae strains with moderate sensitivity to ampicillin or penicillin are fully sensitive to amoxicillin-antibiotic and drug.
To reduce the development of drug-resistant bacteria and maintain the power of drugs and other antibacterial drugs, drugs should be used just to treat or prevent infections that are proven or strongly suspected to be caused by sensitive bacteria. When culture and sensitivity information are available, they are more important in selecting or changing antibacterial therapy.
In the absence of such data, local epidemiology and sensitivity patterns may contribute to the empiric selection of therapy.
the microbial study, to know the causative bacteria-organism and their response to drugs should be performed together with any indicated surgical procedures.
Dosage Augmentin tablet
The dose of augmentin (Amoxicillin 1000 MG / Clavulanate 62.5 MG ) depends on the severity of the disease and age and weight of the patient’s usual dose prescribed for adult one tablet orally BID every 12 hours.
augmentin 1000 tablet Extended-Release Tablet
Side effect Augmentin tablet
Allergic reactions: skin allergy
vasculitis, which may be visible as red or purple raised spots on the skin, but can affect another vessel of the body
fever(high temperature ).
arthralgia, swollen lymph nodes.
angioedema(facial and throat swelling) leads to dyspnea or stridor. collapse.
large intestine inflammation or IBSwatery diarrhea usually bloody or with and mucus, gastric pain, oral candidiasis, nausea and vomiting
less common side effects affect up to .01 people
skin rash, itching
raised itchy rash (hives)
indigestion
dizziness
headache
Rare side effects may occur in .001 patient
skin rash (erythema multiform).
change in clotting time or bleeding time. leucopenia.
lab investigation • increases liver enzymes very rare.
More information
Precaution and toxicity
The amoxicillin-clavulanate suspension (augmentin syrup) has low toxicity of the penicillin group.
But periodic lab investigation including renal, hepatic, and hematopoietic function is advisable if a long period of Augmentin suspension was approved for administration.
A high percentage of patients with mononucleosis who receive ampicillin or augmentin develop an erythematous skin rash.
Ampicillin-class antibiotics shouldn’t be administered to patients with mononucleosis.
The infections with mycotic or bacterial pathogens should be considered during therapy.
If infections occur during treatment as Pseudomonas and Candida.
the drug should be stopped and contact your doctor as soon as possible.
Prescribing AUGMENTIN ES-600 within the absence of a proven or strongly suspected bacterial infection and a prophylactic indication is unlikely to supply benefit to the patient and increases the danger of the development of drug-resistant bacteria.
